聯(lián)系方式

通訊地址：長沙市湘雅路110號，中南大學藥理學系，

郵編：410078

電話：0731-82355078

電子郵件：junpeng@csu.edu.cn

個人簡介

彭軍,男，1968年8月出生，研究員、二級教授，博士生導師,中南大學“升華學者計劃”特聘教授。1991年畢業(yè)于湖南醫(yī)科大學, 1997年獲湖南醫(yī)科大學生物化學碩士學位, 2002年獲中南大學藥理學博士學位。2002-2007年在美國華盛頓州立大學從事博士后工作。現(xiàn)為中南大學湘雅藥學院藥理學系主任，兼任《中國動脈硬化雜志》編委、國際動脈硬化學會中國分會理事、中國動脈硬化專業(yè)委員會委員、中國藥理學學會心血管專業(yè)委員會委員、中藥與天然藥物藥理專業(yè)委員會委員、湖南省藥學會理事、湖南省生理學會常務理事、湖南省藥理學會秘書長等職。

主要方向為內(nèi)源性活性物質(zhì)在心腦血管疾病中作用和機制及藥物防治，已Circulation、Proc. Natl. Acad.Sci. USA、Circ Res、Basic Res Cardiol、Clin Sci等國際權(quán)威和知名期刊發(fā)表論文90余篇，參編教材2部（國家級藥學類規(guī)劃教材《藥理學》）和專5部（《心血管藥理學》、《藥理實驗方法學》等）。先后獲得全國優(yōu)秀博士學位論文獎、湖南省青年科技獎、中華醫(yī)學科技獎、湖南省科學技術(shù)進步獎等多項獎勵。先后主持國家自然科學基金5項(包括重大研究計劃1項)以及美國心臟學會博士后基金、全國優(yōu)博專項基金、教育部博士點基金（博導類）和湖南省自然科學基金重點項目各1項；參與國家“973”計劃項目、國家自然科學基金重點項目、美國NIH項目等多項；2008年入選湖南省普通高校學科帶頭人培養(yǎng)對象，2010年入選湖南省“121”人才工程。

代表作:

1. Zhang YZ, Wang L, Zhang JJ, Xiong XM, Zhang D, Tang XM, Luo XJ, Ma QL,Peng J*(彭軍，通訊作者). Vascular peroxide 1 promotes ox-LDL-induced programmed necrosis in endothelial cells through a mechanism involving β-catenin signaling. Atherosclerosis. 2018; 274:128-138.

2. Zhang YS, Tang LJ, Tu H, Wang SJ, Liu B, Zhang XJ, Li NS, Luo XJ,Peng J*(彭軍，通訊作者). Fasudil ameliorates the ischemia/reperfusion oxidative injury in rat hearts through suppression of myosin regulatory light chain/NADPH oxidase 2 pathway. Eur J Pharmacol. 2018;822:1-12.

3. Zhang JJ, Zhang YZ, Peng JJ, Li NS, Xiong XM, Ma QL, Luo XJ, Liu B,Peng J*(彭軍，通訊作者). Atorvastatin exerts inhibitory effect on endothelial senescence in hyperlipidemic rats through a mechanism involving down-regulation of miR-21-5p/203a-3p. Mech Ageing Dev. 2018; 169:10-18.

4. Tian J, Guo S, Chen H, Peng JJ, Jia MM, Li NS, Zhang XJ, Yang J, Luo XJ,Peng J*(彭軍，通訊作者).Combination of Emricasan with Ponatinib Synergistically Reduces Ischemia/Reperfusion Injury in Rat Brain Through Simultaneous Prevention of Apoptosis and Necroptosis. Transl Stroke Res. 2018; 9(4): 382-392.

5. Peng JJ, Liu B, Xu JY,Peng J*(彭軍，通訊作者), Luo XJ*. NADPH oxidase: its potential role in promotion of pulmonary arterial hypertension. Naunyn Schmiedebergs Arch Pharmacol. 2017; 390(4): 331-338

6. Li TB, Zhang JJ, Liu B, Luo XJ,Ma QL^*,Peng J*(彭軍，通訊作者). Dysfunction of endothelial progenitor cells in hyperlipidemic rats involves the increase of NADPH oxidase-derived reactive oxygen species production. Can J Physiol Pharmacol. 2017; 95(5):474-480.

7. Liu B, Ren KD, Peng JJ, Li T, Luo XJ, Fan C, Yang JF,Peng J*(彭軍，通訊作者).Suppression of NADPH oxidase attenuates hypoxia-induced dysfunctions of endothelial progenitor cells. Biochem Biophys Res Commun. 2017; 482(4):1080-1087.

8. Li JH, Ju GX, Jiang JL, Li NS,Peng J*(彭軍，通訊作者), Luo XJ*. Lipoic acid protects gastric mucosa from ethanol-induced injury in rat through a mechanism involving aldehyde dehydrogenase 2 activation. Alcohol. 2016; 56:21-28. doi: 10.1016/j.alcohol.2016.10.004.

9. Yang ZB, Li TB, Zhang Z, Ren KD, Zheng ZF, Peng J, Luo XJ. The Diagnostic Value of Circulating Brain-specific MicroRNAs for Ischemic Stroke. Intern Med. 2016;55(10):1279-86.

1. Peng J*（彭軍，并列第一）, Ren KD*, Yang J, Luo XJ. Mitochondrial E3 ubiquitin ligase 1: A key enzyme in regulation of mitochondrial dynamics and functions. Mitochondrion. 2016; 28:49-53.

2. Li TB, Zhang JJ, Liu B, Liu WQ, Wu Y, Xiong XM, Luo XJ, Ma QL,Peng J*(彭軍，通訊作者).Involvement of NADPH oxidases and non-muscle myosin light chain in senescence of endothelial progenitor cells in hyperlipidemia. Naunyn Schmiedebergs Arch Pharmacol. 2016; 389(3):289-302.

3. Wu Y, Zhang JJ, Li TB, Liu WQ, Li LS, Luo XJ, Jiang JL, Ma QL, Yang ZC,Peng J*(彭軍，通訊作者).Phosphorylation of Nonmuscle Myosin Light Chain Promotes Endothelial Injury in Hyperlipidemic Rats Through a Mechanism Involving Downregulation of Dimethylarginine Dimethylaminohydrolase 2. J Cardiovasc Pharmacol Ther. 2016; 21(6):536-548.

4. Liu B, Li T, Peng JJ, Zhang JJ, Liu WQ, Luo XJ, Ma QL, Gong ZC,Peng J*(彭軍，通訊作者). Non-muscle myosin light chain promotes endothelial progenitor cells senescence and dysfunction in pulmonary hypertensive rats through up-regulation of NADPH oxidase. Eur J Pharmacol. 2016;775:67-77.

5. YangZB, LuoXJ, RenKD, PengJJ, TanB, LiuB, LouZ, XiongXM, ZhangXJ, Ren X,Peng J*(彭軍，通訊作者). Beneficial effect of magnesium lithospermate B on cerebral ischemia-reperfusion injury in rats involves the regulation of miR-107/glutamate transporter 1 pathway. Eur J Pharmacol. 2015; 766: 91-98.

6. Zhang HF, Li TB, Liu B, Lou Z, Zhang JJ, Peng JJ, Zhang XJ, Ma QL,Peng J*, Luo XJ. Inhibition of myosin light chain kinase reduces NADPH oxidase-mediated oxidative injury in rat brain following cerebral ischemia/reperfusion. Naunyn Schmiedebergs Arch Pharmacol. 2015; 388(9): 953-632.

7. Zhang YS, Liu B, Luo XJ, Li TB, Zhang JJ, Peng JJ, Zhang XJ, Ma QL, Hu CP, Li YJ,Peng J*(彭軍，通訊作者), Li Q. Nuclear cardiac myosin light chain 2 modulates NADPH oxidase 2 expression in myocardium: a novel function beyond muscle contraction. Basic Res Cardiol. 2015;110(4):38

8. Zhang YS, Liu B, Luo XJ, Zhang JJ, Li NS, Ma QL, Jiang JL, Li YJ, Li Q,Peng J*(彭軍，通訊作者). A novel function of nuclear nonmuscle myosin regulatory light chain in promotion of xanthine oxidase transcription after myocardial ischemia/reperfusion. Free Radic Biol Med. 2015; 83:115-128.

9. Peng J(彭軍), Liu B, Ma QL, Luo XJ. Dysfunctional endothelial progenitor cells in cardiovascular diseases: role of NADPH oxidase. J Cardiovasc Pharmacol. 2015; 65(1):80-7.

10. Luo XJ, Liu B, Ma QL,Peng J*(彭軍，通訊作者). Mitochondrial AldehydDehydrogenase, a Potential Drug Target for Protection of Heart and Brain from Ischemia/Reperfusion Injury. Curr Drug Targets. 2014;15(10): 948-55.

11. Yang ZB, Zhang Z, Li TB, Lou Z, Li SY, Yang H, Yang J, Luo XJ,Peng J*(彭軍，通訊作者). Up-regulation of brain-enriched miR-107 promotes excitatory neurotoxicity through down-regulation of glutamate transporter-1 expression following ischaemic stroke. Clin Sci (Lond). 2014;127(12):679-89.

12. Ma QL, Zhang GG,Peng J*(彭軍，通訊作者). Vascular Peroxidase 1: a Novel Enzyme in Promoting Oxidative Stress in Cardiovascular System. Trends Cardiovasc Med, 2013, 23: 179-183.

13. Zhang YS, He L, Liu B, Li NS, Luo XJ, Hu CP, Ma QL, Zhang GG, Li YJ,Peng J*(彭軍，通訊作者). A novel pathway of NADPH oxidase/vascular peroxidase 1 in mediating oxidative injury following ischemia – reperfusion. Basic Res Cardiol, 2012, 107(3):266.

14. He L, Liu B, Dai Z, Zhang HF, Zhang YS, Luo XJ, Ma QL,Peng J* (彭軍，通訊作者). Alpha lipoic acid protects heart against myocardial ischemia-reperfusion injury through a mechanism involving aldehyde dehydrogenase 2 activation. Eur J Pharmacol. 2012; 678(1-3):32-8.

15. Peng J(彭軍), Raddatz K, Molkentin JD, Yiming Wu, Granzier H, Gotthardt M. Cardiac hypertrophy and reduced contractility in hearts deficient in titin kinase region. Circulation,2007, 115(6):743-51.