余鵬，博士，副教授，中南大學(xué)湘雅藥學(xué)院碩士研究生導(dǎo)師。主要研究方向?yàn)樯锓肿幼R(shí)別的機(jī)制研究及應(yīng)用開發(fā)，發(fā)表高水平學(xué)術(shù)論文300余篇，其中以第一作者/通訊作者發(fā)表56篇，申請(qǐng)專利28項(xiàng)，已授權(quán)7項(xiàng)，主持及參與國(guó)家、省、市等各級(jí)科研項(xiàng)目22項(xiàng)，指導(dǎo)學(xué)生獲獎(jiǎng)22項(xiàng)。

聯(lián)系方式：

手機(jī)：13348716587

電子郵箱：peng.yu@csu.edu.cn

近5年承擔(dān)課題：

1. 湖南省自然科學(xué)基金——科藥聯(lián)合基金基于核酸適配體的手性藥物拆分方法的理論可行性研究（2022JJ80105）。執(zhí)行年限：2022.1-2024.12.

2. 湖南省自然科學(xué)基金項(xiàng)目，基于生物質(zhì)譜法定量耐藥細(xì)胞轉(zhuǎn)運(yùn)蛋白表達(dá)量的方法建立及其在檢測(cè)腫瘤細(xì)胞耐藥指數(shù)上的應(yīng)用（2018JJ2415）。執(zhí)行年限：2018.1-2020.1.

3. 2018年師生共創(chuàng)立項(xiàng)項(xiàng)目，癌癥個(gè)體化用藥技術(shù)平臺(tái)-基于人工智能的精準(zhǔn)給藥（2018gczd032）。執(zhí)行年限：2018.11-2019.12.

近5年發(fā)表論文：

[1]Jie Y ,Xiaoling L ,Meilun C , et al.Non-immobilized GO-SELEX screening of aptamers against cyclosporine A and its application in a AuNPs colorimetric aptasensor.[J].Analytical methods : advancing methods and applications,2023, IF=3.1,JCR分區(qū)：Q2

[2]Yijie L ,Xiaoling L ,Meilun C , et al.Advances in screening, synthesis, modification, and biomedical applications of peptides and peptide aptamers.[J].BioFactors (Oxford, England),2023, IF=6.0,JCR分區(qū)：Q1

[3]Yijie L ,Jie Y ,Meilun C , et al.Recent advances in computer-aided virtual screening and docking optimization for aptamer.[J].Current topics in medicinal chemistry,2023,23(20):1985-2000.IF=3.041,JCR分區(qū)：Q1

[4]Hanbing J ,Jie Y ,Yucui H , et al.Evaluation of intracellular metabolism of methotrexate in hepatocytes and embryonic kidney cells based on Folylpolyglutamate Synthetase and gamma-Glutamyl Hydrolase expression.[J].Current drug metabolism,2023,24(2),IF=3.408,JCR分區(qū)：Q2

[5]Yucui H ,Xiaoling L ,Jie Y , et al.A label-free fluorescent aptamer sensor for testosterone based on SYBR Green I.[J].Analytical methods : advancing methods and applications,2023,15(12),IF=3.1,JCR分區(qū)：Q2

[6]Huanhuan Li, Tongji Cai, Yi Ren, Jing Huang, Hanbing Jiang, Yucui Hou, Chunhua Tang, Jie Yang, Jia Zhao，Peng Yu *. A simple unlabeled human chorionic gonadotropin biosensor based on a peptide aptamer. Analytical Methods，7 Sep 2021. doi: 10.1039/d1ay01105g. IF=2.596; JCR分區(qū)：Q2

[7]Zhonghua Ouyang , Jing Huang, Yi Ren, Huanhuan Li, Yao Ding, Ke Zhang, Lei Jiang, Peng Yu*.(2021).Studies on the intracellular accumulation process of methotrexate and its correlation with the key protein using an LC-MS/MS method: a novel way to realize prospective individualized medication.. Analytical and bioanalytical chemistry，Mar 2021, 413: 1799-1807. doi:10.1007/S00216-020-03125-2. IF=3.63; JCR分區(qū)：Q1

[8]Yi Ren, Yao Ding, Fanqi Meng, Lei Jiang, Huanhuan Li, Jing Huang, Peng Yu*, Zhaohui Qiu*. Quantification of CYP2E1 in rat liver by UPLC-MS/MS-based targeted proteomics assay: a novel approach for enzyme activity assessment. Analytical and bioanalytical chemistry，25 June 2020. doi:10.1007/s00216-020-02757-8. IF=3.637; JCR分區(qū)：Q1

[9]Huanhuan Li, Fanqi Meng, Lei Jiang, Zhaohui Qiu, Peng Yu*. Comparison of LC-MS/MS-based targeted proteomics and conventional analytical methods for monitoring breast cancer resistance protein expression. Life Sciences. 231(2019). IF= 3.448; JCR分區(qū)：Q1

[10]Lei Jiang, Fanqi Meng, Zhaohui Qiu, Ke Zhang, Yao Ding, Huanhuan Li, Yi Ren, Peng Yu*, Jie Peng. Comparison of UPLC-MS/MS-based targeted quantitation and conventional quantitative methods for the analysis of MRP1 expression in tumor cell lines. Journal of Chromatography B. 2019, 1109:10-18. IF= 2.813; JCR分區(qū)：Q2

近5年獲批專利：

1. 余鵬、江寒冰、張可、丁堯；一種預(yù)測(cè)甲氨蝶呤藥效的肽段組合物及其定量檢測(cè)方法與檢測(cè)試劑盒，2021.03.26，中國(guó)，ZL201911064881.2

2. 余鵬、李歡歡、孟凡奇、蔣蕾、任藝；甲氨蝶呤給藥方案確定方法、裝置、儲(chǔ)存介質(zhì)及設(shè)備，2019.05.14，中國(guó)，CN109754858A

3. 余鵬、蔣蕾、孟凡奇、丁堯；用于FPGS和GGH蛋白表達(dá)量檢測(cè)的特征性多肽及其應(yīng)用，2021.03.26，中國(guó)，ZL201910711103.1

4. 余鵬、蔣蕾、孟凡奇；一種估算齊多夫定藥時(shí)曲線下面積的方法，2020.01.10，中國(guó)，CN110675961A